Our
Third International Conference was rated a great success by the over 100 delegates
who attended.The venue was the historic Royal
Society, Carlton House Terrace, London, SW1, which celebrates the achievements
of British Scientists for over five hundred years. Established since 1660, the
Royal Society has been at the forefront of scientific enquiry and discovery and
has promoted the advance of science, engineering and technology worldwide. Among
the eminent members of the Society have been Isaac Newton, Charles Darwin, Ernest
Rutherford, Albert Einstein, Dorothy Hodgkin and Stephen Hawking. We felt honoured
to be there, and the building added a dramatic sense of occasion.
The
theme of the meeting was Androgens and Mens Health and the presentations
demonstrated ever more clearly, the extensive and vital role of male hormones
in developing, maintaining and protecting health throughout life.
If
you ever thought testosterone was only about sex, you need to change that view
right now, as within the overall body of scientific work there were a number of
sub-themes which clearly illustrated the multiplicity of essential functions to
which androgens are necessary.
The importance
of androgens in Primary Care Medicine was the theme emerging from the papers of
Prof. Louis Gooren, (primary care) Prof. Richard Eastell, (bone) Prof. Jesper
Mehlesen (peripheral circulation) and Dr. Tom Trinick (diabetes).
The
theme of metabolism also present in Dr. Tom Trinicks work was echoed in
poster presentations from Dr. Svetlana Kalintchenko, Prof. Andrzej Gomula, and
Dr. Neil Burman.
Not the most popular of topics
at present , it seems, and yet the emerging work on the involvement of androgens
in the function of the brain and the link between androgen deficiency and Alzheimers
Disease may prove to be one of the most significant. According to this years
report from the Alzheimers Research Trust, over the next 30 years, the number
of patients suffering from dementia, of which two thirds will be Alzheimer sufferers,
is set to nearly double to three quarters of a million in the UK.
This
will clearly have significant financial implications for the British NHS and for
health services worldwide. In the UK alone, the budget for care of Alzheimers
patients will increase from £3.3 billion to £7.9 billion by 2031.
An
androgen based solution to prevention or treatment of this and related conditions
would be a major breakthrough. Papers by Dr. Eva Hogervorst, Prof. Suzanna Petancesca,
Prof. Lorenzo Refolo, Prof. Robert Tan and Prof. Ralph Martins examine the evidence
in this area of research.
Prostate function and
prostate cancer is a continuing area of interest for the majority of doctors.
This was highlighted by the presentations from Mr. Mark Feneley, Prof. Aksam Yassin
and Dr. Joel Kaufman. Reassurance about the safety of prescribing testosterone
in patients recovering from prostate cancer and the emerging notion that low testosterone
levels may be a contributory factor in development of this condition, were some
of the issues which were covered in this theme.
Sexual
function, not surprisingly, was also a topic of interest, with poster presentations
by Dr. Stefan Uekert (plasma testosterone levels) and Dr. Alfredo Belzuzarri looking
at the possibility of web diagnosis of erectile dysfunction.
Nor
were the evergreen controversies around diagnosis of the andropause absent. Prof.
Bruno Lunenfeld, covered the current European recommendations for diagnosis, in
his outstanding presentation, and posters by Dr. Clement Williams, Prof. Juha
Makinen and Dr. Neil Burman also explored aspects of this topic.
Prof.
Lunenfeld, Clem Williams and Dr. Bruce Biundo went on to consider aspects of hormonal
replacement in men, including safety issues and characteristics of different hormonal
preparations.
Finally, posters by Prof. Andrzej
Gomula and joint authors, Dr. Romil Stanislavov and Mrs. Vessela Nikolova from
Bulgaria, contributed to the more controversial theme of possible approaches to
anti-aging.
In the last pleniary session of the
conference, delegates from the seventeen countries represented at the conference
spoke of the clinical work going on in their countries, and how this could be
helped by TAS.
In particular, the need for a teaching
course on the diagnosis and treatment of androgen deficiency was emphasized by
the delegates. It was agreed that this would be one of the major goals of TAS
over the coming year.
Abstracts of the conference
papers, and the speakers details, are now available on line.
Dr
Malcolm Carruthers MD FRC Path MRCGP
Chairman
of The Andropause Society