|
| References
- Testosterone, the brain and psyche |
6.
Seidman SN,.Walsh BT. Testosterone and depression
in aging men. Am.J.Geriatr.Psychiatry 1999;7:18-33.
Abstract: In men, testosterone secretion affects neurobehavioral
functions such as sexual arousal, aggression, emotional tone,
and cognition. Beginning at approximately age 50, men secrete
progressively lower amounts of testosterone; about 20% of
men over age 60 have lower-than-normal levels. The psychiatric
sequelae are poorly understood, yet there is evidence of an
association with depressive symptoms. The authors reviewed
1) the physiology of the hypothalamic-pituitary-gonadal axis
and its changes with age in men; and 2) the evidence linking
testosterone level and major depression in men. Data on this
relationship are derived from two types of studies: observational
studies comparing testosterone levels and secretory patterns
in depressed and non-depressed men, and treatment studies
using exogenous androgens for male depression. The data suggest
that some depressed older men may have state-dependent low
testosterone levels and that some depressed men may improve
with androgen treatment
|
| back
to reference list - Testosterone, Brain and Psyche |
| back
to reference library menu |
|
|
|
