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| References
- Vasectomy |
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14.
Alexander NJ, Fulgham DL, Plunkett ER, Witkin SS. Antisperm
antibodies and circulating immune complexes of vasectomized
men with and without coronary events. Am J Reprod Immunol
Microbiol. 1986;12:38-44.
Abstract:
We compared antisperm antibody and circulating immune complex
(CIC) levels in serum samples from 101 vasectomized and 101
normal age-matched nonvasectomized men; 31 of each group had
histories of coronary heart disease (CHD). Vasectomy and CHD
status were treated as categorical independent variables in
the two-way analysis of variance. Elevations of both systolic
and diastolic blood pressures were significantly associated
with age and body mass index but not vasectomy. Antisperm
antibodies (immobilizing and agglutinating) were significantly
associated with vasectomy (P less than or equal to .001);
the incidences were similar in men with and without CHD. The
CICs were significantly associated with vasectomy in a Staphylococcus
aureus (FcSa) CIC assay (P less than or equal to .001) and
a Raji cell CIC assay (P less than or equal to .05). A third
CIC assay, the Clq binding assay, did not reveal a difference
between any subgroups. Generally, CICs occurred more frequently
in the CHD group by the FcSa assay and particularly the Raji
cell assay (P less than or equal to .001). In summary, vasectomized
men had a higher incidence and higher levels of circulating
antisperm autoantibodies and CICs than did age-matched controls
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