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| References
- Vasectomy |
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20.
Moller H, Knudsen LB, Lynge E. Risk of testicular cancer after
vasectomy: cohort study of over 73,000 men. BMJ 1994;309:295-9.
Abstract:
OBJECTIVE--To confirm or refute reports that vasectomy may
increase the risk of cancers of the testis and prostate. DESIGN--Computerised
record linkage study of cohort of men with vasectomy and comparison
of cancer rates with those in the whole Danish population;
manual check of all records of patients with testicular and
prostate cancer diagnosed within the first year of follow
up. SETTING--Denmark 1977-89. SUBJECTS--Cohort of 73,917 men
identified in hospital discharge and pathology registers as
having had a vasectomy for any reason during 1977-89. MAIN
OUTCOME MEASURES--Observed incidences of testicular, prostate,
and other cancers up to the end of 1989. RESULTS--The overall
pattern of cancer incidence in the study cohort was similar
to that expected nationally. No increased incidence in testicular
cancer was observed (70 cases; standardised morbidity ratio
1.01 (95% confidence interval 0.79 to 1.28)). The incidence
during the first year of follow up was also close to that
expected (nine cases; standardised morbidity ratio 0.80 (0.36
to 1.51)). The incidence of prostate cancer was not increased
(165 cases; standardised morbidity ratio 0.98 (0.84 to 1.14)).
CONCLUSIONS--The incidence of testicular cancer in men with
vasectomy is no higher than in other men. Vasectomy does not
cause testicular cancer and does not accelerate the growth
or diagnosis of pre-existing testicular neoplasms. Data concerning
a causal relation between vasectomy and prostate cancer were
inconclusive
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