21.
Hewitt G, Logan CJ, Curry RC. Does vasectomy cause testicular
cancer? Br.J.Urol. 1993;71:607-8.
Abstract:
Between 1975 and 1990, 330 men developed testicular tumours
in Northern Ireland. Their names were cross matched with
a sample of 2904 men who had undergone vasectomy between
1970 and 1985. The expected numbers of tumours in vasectomised
patients was 2, while the actual number was 1. Our experience
does not indicate that vasectomy causes testicular cancer
22. Jorgensen N, Giwercman A, Hansen SW, Skakkebaek NE.
Testicular cancer after vasectomy: origin from carcinoma
in situ of the testis. Eur.J Cancer 1993;29A:1062-4. Abstract:
Vasectomy is a commonly used male contraceptive procedure.
Reports have indicated that vasectomy is associated with
an increased risk of development of germinal testicular
cancer. Carcinoma in situ of the testis (CIS) is a preinvasive
lesion which precedes germinal testicular cancer. CIS is
almost always found in the tissue adjacent to a germinal
testicular cancer. It is believed that CIS is a malignant
gonocyte formed during embryogenesis. We have studied the
testicular tissue from 5 previously vasectomised patients
with testicular cancer and found CIS in the tissue adjacent
to their cancer as well as changes in the epididymis of
the patients. We discuss the findings and conclude that
testicular cancers occurring after vasectomy is not an exception
from the rule that testicular cancer originates from CIS.
Thus, there is no causal relationship between vasectomy
and testicular cancer, but vasectomy might precipitate the
development of testicular cancer from the preinvasive CIS
lesion
